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HUMANIZED ANTI-BASIGIN ANTIBODIES AND USE OF THE SAME

机译:人源抗巴希菌素抗体及其使用

摘要

The present invention relates to a humanized anti-basigin antibody or antigen binding fragment thereof comprising the heavy chain variable region (vh) comprising an amino acid sequence of seq id: 1; optionally also comprises the light chain variable region (v1) comprising an amino acid sequence of sequence id: 2.The present invention also relates to a composition comprising the humanized anti-basigin antibody or antigen-binding fragment thereof, an isolated nucleic acid sequence encoding the humanized anti-basigin antibody or antigen-binding fragment thereof, a vector. comprising the nucleic acid, a host cell comprising the vector, and the use of the humanized anti-basigin antibody or antigen binding fragment thereof.
机译:本发明涉及一种人源化抗-basigin抗体或其抗原结合片段,其包含重链可变区(vh),所述重链可变区的氨基酸序列为seq id:1;和任选地还包含轻链可变区(v1),其包含序列id:2的氨基酸序列。本发明还涉及一种组合物,其包含人源化的抗-basigin抗体或其抗原结合片段,编码人源化的抗-basigin抗体或其抗原结合片段的分离的核酸序列,载体。包含核酸的载体,包含载体的宿主细胞,以及人源化抗-basigin抗体或其抗原结合片段的用途。

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