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Humanized anti-BASIGIN antibodies and uses thereof

机译:人源化抗BASIGIN抗体及其用途

摘要

The present disclosure relates to a heavy chain variable region (V H ) comprising the amino acid sequence of SEQ ID NO: 1; BASIGIN antibody or antigen-binding fragment thereof, optionally further comprising a light chain variable region (V L ) comprising the amino acid sequence of SEQ ID NO: 2. The disclosure also provides a composition comprising a humanized anti-BASIGIN antibody or antigen-binding fragment thereof, an isolated nucleic acid sequence encoding a humanized anti-BASIGIN antibody or antigen-binding fragment thereof, a vector comprising said nucleic acid, Host cell, and a humanized anti-BASIGIN antibody or antigen-binding fragment thereof.
机译:本公开涉及包含SEQ ID NO:1的氨基酸序列的重链可变区(V H )。 BASIGIN抗体或其抗原结合片段,任选地进一步包含包含SEQ ID NO:2的氨基酸序列的轻链可变区(V L )。本公开内容还提供了包含人源化抗-BASIGIN抗体或其抗原结合片段,编码人源化抗BASIGIN抗体或其抗原结合片段的分离的核酸序列,包含所述核酸的载体,宿主细胞和人源化抗BASIGIN抗体或抗原结合其片段。

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