lactobacillus rhamnosus bacteria with antifungal activity, their use, composition, food, feed or pharmaceutical, as well as methods of producing a fermented dairy product, food, feed or pharmaceutical

摘要

Lactobacillus rhamnosus bacteria with antifungal activity, use thereof, composition, food, feed or pharmaceutical product as well as methods of producing a fermented dairy product, food, feed or pharmaceutical product The present invention relates to a bacterium of the species lactobacillus fermentum having the ability to inhibit the growth of the fungus penicillium solitum deposited under no. Accessibility: dsm32093 or the growth of the fungus penicillium brevicompactum deposited under no. Accessibility: dsm32094 for at least 50%. inhibitory activity may be determined in an assay comprising: (1) preparing a fermented milk product by: (a) inoculating a milk with lactobacillus fermentum at a concentration of at least 107 cfu / g and with a starter culture; (b) fermentation to a pH of 4.6 is reached, and (c) solidification of fermented milk by addition of agar; (2) generate at least one dust spot. solitum or p. brevicompactum on solidified fermented milk agar with a concentration of 500 spores / spot and incubating for 7 days at 25 ° C; (3) determine the inhibition percentage by determining the largest diameter of the colony formed by p growth. solitum or p. brevicompactum and expressing diameter as a percentage of the largest diameter formed under the same conditions, but in the absence of the lactobacillus fermentum strain. The invention further relates to compositions comprising the bacterium, methods for producing fermented dairy products using the bacterium and products obtained therefrom.