METHOD FOR PREPARATION OF A MICROFLUIDIZED WATER OIL EMULSION IN THE SUBMICROMETER RANGE WITH A LOWER MEDIUM OIL GULIC SIZE AT 0.5? MICROFLUIDIZED VACCINE

摘要

"microfluidized oil-in-water emulsions and vaccine compositions". This invention features oil-in-water emulsions in the submicron range usable as a vaccine adjuvant to increase antigen immunogenicity. The present invention also provides vaccine compositions containing an antigen associated with such emulsions intrinsically or extrinsically. Also disclosed herein are methods of preparing emulsions and vaccines.