Yp1 inhibitors manage the interaction between yp1 and Neos

摘要

Yp1 simultaneous interpreter is combined with Sox2 conversion factor induced by Neos, which is a transcriber for self-renewal of NSCs. Yap1's WW domain name is combined with ppxy Neo motivation to induce Sox2. A peptide corresponding to the WW domain is provided to prevent Sox2 induction and stem cell characterization. Similarly, ppxy motivated peptides and oil also have the ability to inhibit stem cell characteristics. It describes the compounds that affect the interaction of yp1: Oct4.