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Solid dispersion with improved solubility comprising tetrazole derivative as an active ingredient
Solid dispersion with improved solubility comprising tetrazole derivative as an active ingredient
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机译:具有改善的溶解度的固体分散体,包含四唑衍生物作为活性成分
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摘要
The present invention relates to an amorphous solid dispersion comprising a tetrazole derivative of the formula (I) or a pharmaceutically acceptable salt thereof as an active ingredient. The solid dispersion of the present invention comprises a water-soluble polymer or an acid so as to improve the solubility of its active ingredient, i.e., the tetrazole derivative of the formula (I), thereby improving its absorption rate, and thus can be effectively used to reduce multi-drug resistance (MDR) in cancer cells.
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