首页> 外国专利> TREATMENT OF PROSTATE CANCER AND A METHOD FOR DETERMINING THE PROGNOSIS FOR PROSTATE CANCER PATIENTS

TREATMENT OF PROSTATE CANCER AND A METHOD FOR DETERMINING THE PROGNOSIS FOR PROSTATE CANCER PATIENTS

机译:前列腺癌的治疗方法和确定前列腺癌患者预后的方法

摘要

The present invention relates to a Wnt5a protein or peptide thereof possessing Wnt5a signaling properties, such as Foxy5, for use in the treatment of prostate cancer, in particular in patients that have undergone or will undergo radical prosteatectomy. The invention also relates to a method for determining a prognosis for a patient having prostate cancer and a kit for performing said method. The method for determining a prognosis for a patient comprises the steps of: evaluating an amount of Wnt5a protein present in at least part of a sample earlier obtained from the patient and determining a sample value corresponding to the evaluated amount; comparing the sample value obtained in step a) with a reference value associated with a reference prognosis; and, if said sample value is higher than said reference value, concluding that the prognosis for said patient is better than said reference prognosis.
机译:本发明涉及具有Wnt5a信号传导性质的Wnt5a蛋白或其肽,例如Foxy5,其用于治疗前列腺癌,特别是在已经或将要进行根治性前列腺切除术的患者中。本发明还涉及用于确定患有前列腺癌的患者的预后的方法和用于执行所述方法的试剂盒。用于确定患者的预后的方法包括以下步骤:评估至少一部分较早地从患者获得的样品中存在的Wnt5a蛋白的量,并确定与所评估的量相对应的样品值;以及将步骤a)中获得的样本值与与参考预后相关的参考值进行比较;如果所述样本值高于所述参考值,则认为所述患者的预后好于所述参考预后。

著录项

  • 公开/公告号PL2726880T3

    专利类型

  • 公开/公告日2019-09-30

    原文格式PDF

  • 申请/专利权人 WNTRESEARCH AB;

    申请/专利号PL20120807837T

  • 发明设计人 ANDERSSON TOMMY;BJARTELL ANDERS;

    申请日2012-06-28

  • 分类号G01N33/574;A61K38/17;A61P13/08;A61P35;

  • 国家 PL

  • 入库时间 2022-08-21 12:01:18

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