2,5-di(selenophen-2-yl)-4-methyl-4-octyl-dithienosilole - derivative of dithienosilole, method for obtaining it and enzyme substrate electrode for detection of estriol

摘要

the application concerns ditienosilolu derivative, which is from 2.5 - di (selenofen - 2 - yl) - 4 - methyl - 4 - octyl - ditienosilol model 1, intended to modify the equipment sensorowych.the application also includes a way to produce 2,5 - di (selenofen - 2 - yl) - 4 - methyl - 4 - octyl - ditienosilolu of model 1 is thatin the first stage is carried out by connecting the ring closure reaction tiofenowego in positions of beta.beta. - silicon atom designated two different groups propenoates: methyl and n - oktylową, creating the trójcykliczny flat configuration using 3,3 '- dibromo-4,4 - 5,5' - bis (trimethylsilyl) - 22 '- bitiofenu, oktylometylo - dichlorosilanu and n -'s, then the bromine to 4 - octyl - 4 - ethyl - ditienosilolu reaction with nbs in tetrahydrofuran at room temperature.of the 24 hours, after which the moving reaction stille's 4.4 '- dibromotetrafenylosilanu with 2 - (tributylocyno) selenofenem, in an atmosphere of nitrogen inertnej, in an anhydrous tetrahydrofuran, using palladium catalyst (pdcl2 (pph3) 2).the application also relates to enzyme electrodes to detect estriol.which contains an active layer in the form of a protein on the surface of tyrozynazy zimmobilizowanej elektroprzewodzącego film obtained from 2,5 - di (selenofen - 2 - yl) - 4 - methyl - 4 - octyl - ditienosilolu.