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A METHOD FOR TARGET PROTEIN IDENTIFICATION USING THERMAL STABILITY SHIFT-BASED FLUORESCENCE DIFFERENCE IN TWO-DIMENSIONAL GEL ELECTROPHORESIS
A METHOD FOR TARGET PROTEIN IDENTIFICATION USING THERMAL STABILITY SHIFT-BASED FLUORESCENCE DIFFERENCE IN TWO-DIMENSIONAL GEL ELECTROPHORESIS
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机译:二维凝胶电泳中基于热稳定性漂移的荧光差异的目标蛋白质识别方法
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摘要
The present invention relates to a method for identifying a target protein using a thermal stability shift-based fluorescence difference in two-dimensional gel electrophoresis, and more specifically, a method for identifying a protein, which is a target of a specific drug, by analyzing, by means of a fluorescence difference in two-dimensional gel electrophoresis, a thermal stability shift in the protein when a specific drug, preferably a bioactive molecule, binds to the target protein.
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