Overexpression of methionine aminopeptidase in peripheral blood and peripheral blood mononuclear cells is a marker for the detection, diagnosis and prognosis of colorectal cancer

摘要

A screening method for colorectal cancer (CRC) comprising: detecting levels of methionine aminopeptidase 2 (MetAP2) in a non-tumor sample of an individual at risk of developing CRC, said non-tumor sample being chosen from the group consisting of peripheral blood , peripheral blood mononuclear cells (PBMC), neutrophils and lymphocytes; and determining if MetAP2 levels are above a threshold value, where MetAP2 levels above the threshold value indicate that the individual is examined for CCR.