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Conjugates of multivalent cell penetration proteins and peptides and their uses
Conjugates of multivalent cell penetration proteins and peptides and their uses
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机译:多价细胞渗透蛋白和肽的结合物及其用途
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摘要
The present invention relates to conjugates comprising a protein and multivalent cell-penetrating peptide(s), each multivalent cell-penetrating peptide comprising at least two cell-penetrating peptides, wherein the multivalent cell-penetrating peptide(s) is/are covalently attached to the protein. The present invention furthermore relates to a method of generating the conjugates and to their medical uses, in particular their use in the diagnosis, prevention and/or treatment of diseases. The present invention relates to methods of diagnosis, prevention and/or treatment of diseases, comprising administering the conjugates of the invention to a patient.
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