首页> 外国专利> TREATMENT OF SEX HORMONE BINDING GLOBULIN (SHBG) RELATED DISEASES BY INHIBITION OF NATURAL ANTISENSE TRANSCRIPT TO SHBG

TREATMENT OF SEX HORMONE BINDING GLOBULIN (SHBG) RELATED DISEASES BY INHIBITION OF NATURAL ANTISENSE TRANSCRIPT TO SHBG

机译：通过抑制自然反义转录为SHBG来治疗性激素结合球蛋白（SHBG）相关疾病

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摘要

The present invention relates to antisense oligonucleotides that modulate the expression of and/or function of Sex Hormone Binding Globulin (SHBG), in particular, by targeting natural antisense polynucleotides of Sex Hormone Binding Globulin (SHBG). The invention also relates to the identification of these antisense oligonucleotides and their use in treating diseases and disorders associated with the expression of SHBG.

机译：本发明涉及调节性激素结合球蛋白（SHBG）的表达和/或功能的反义寡核苷酸，特别是通过靶向性激素结合球蛋白（SHBG）的天然反义多核苷酸。本发明还涉及这些反义寡核苷酸的鉴定及其在治疗与SHBG表达有关的疾病和病症中的用途。

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公开/公告号CA2786535C

专利类型
公开/公告日2019-03-26

原文格式PDF
申请/专利权人 CURNA INC.;
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申请/专利号CA20112786535
发明设计人 COLLARD JOSEPH;KHORKOVA SHERMAN OLGA;
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申请日2011-01-11
分类号C12N15/113;A61K31/7088;A61K48;C12N15/63;
国家 CA
入库时间 2022-08-21 11:59:15

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