METHOD FOR EVALUATING TUBERCULOSIS ONSET RISK SPECIFICALLY TO GENETIC LINEAGE OF MYCOBACTERIUM TUBERCULOSIS

摘要

Provided is a method for evaluating an onset risk of tuberculosis on the basis of genetic information of a subject, said subject being infected with Mycobacterium tuberculosis, specifically to each genetic lineage of M. tuberculosis. The method comprises: identifying a base at a single nucleotide polymorphic site in the subject's genome relating to the onset of tuberculosis in the subject; typing the genetic lineage of M. tuberculosis latently infecting the subject; and then determining the risk of the onset of tuberculosis caused by the latently infecting M. tuberculosis in the subject specifically to the genetic lineage of M. tuberculosis.