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Combination of a PD-l antagonist and a RAF inhibitor for treating cancer

机译:PD-1拮抗剂和RAF抑制剂的组合用于治疗癌症

摘要

Disclosed herein is a pharmaceutical combination for use in the prevention, delay of progression or treatment of cancer, wherein the pharmaceutical combination exhibits a synergistic efficacy. The pharmaceutical combination comprises a humanized antagonist monoclonal antibody against PD- and a RAF inhibitor. Also disclosed herein is a combination for use in the prevention, delay of progression or treatment of cancer in a subject, comprising administering to the subject a therapeutically effective amount of a humanized antagonist monoclonal antibody against PD-1 and a therapeutically effective amount of a RAF inhibitor.
机译:本文公开了用于预防,延迟疾病进展或治疗癌症的药物组合,其中所述药物组合表现出协同功效。该药物组合包含针对PD-的人源化拮抗剂单克隆抗体和RAF抑制剂。本文还公开了用于在受试者中预防,延缓其进展或治疗癌症的组合,其包括向受试者施用治疗有效量的针对PD-1的人源化拮抗剂单克隆抗体和治疗有效量的RAF。抑制剂。

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