COPY NUMBER MEASUREMENT DEVICE, COPY NUMBER MEASUREMENT PROGRAM,COPY NUMBER MEASUREMENT METHOD AND GENE PANEL

摘要

According to the present invention, a position specifying unit (110) maps a plurality of tumor sample reads to a human genome array and specifies a target position which is a genome position of a base being changed with respect to the human genome array for each target gene. A frequency calculation unit (120) calculates a mutant allele frequency for each target position of each target gene. A distance calculation unit (130) calculates a feature distance corresponding to the difference between a reference mutant allele frequency and the mutant allele frequency corresponding to the peak density in a density distribution that indicates the density for the mutant allele frequency of the number of mapping reads for each target gene. The coefficient calculation unit (140) calculates a correction coefficient by using the feature distance for each target gene. The copy number calculation unit (150) calculates a copy number for each target gene in a cancer cell by using the copy number and the correction coefficient for each target gene in a tumor sample.