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THERAPEUTIC APPROACHES FOR THE TREATMENT OF BACTERIAL INFECTIONS

机译:细菌感染的治疗方法

摘要

The present invention refers to an immunogenic fragment of a protein comprising a sequence with at least a 95% identity with SEQ ID NO: 1, also wherein said fragment has a molecular weight of 2 to 120kDa; also to the use of a protein comprising a sequence with at least a 95% identity with SEQ ID NO: 1 or said fragment for use as immunogen. The invention also refers to an antibody that specifically binds to said protein or fragment thereof, and the uses of them in the treatment and/or prophylaxis of a bacterial infectious disease and as antibiotic resistance inhibitor.
机译:本发明涉及蛋白质的免疫原性片段,其包含与SEQ ID NO:1具有至少95%同一性的序列,其中所述片段的分子量为2至120kDa。还涉及包含与SEQ ID NO:1或所述片段具有至少95%同一性的序列的蛋白质用作免疫原的用途。本发明还涉及与所述蛋白质或其片段特异性结合的抗体,以及它们在治疗和/或预防细菌感染性疾病中以及作为抗生素抗性抑制剂的用途。

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