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methods for treating a bacterial infection, for preventing, treating or ameliorating the effective treatment of mrsa, for inhibiting the growth of a microbe, and for selecting a mrsa therapeutic agent useful for treating a bacterial infection, and, composition.
methods for treating a bacterial infection, for preventing, treating or ameliorating the effective treatment of mrsa, for inhibiting the growth of a microbe, and for selecting a mrsa therapeutic agent useful for treating a bacterial infection, and, composition.
The disclosure provides a molecular genetic approach of targeted mutagenesis and heterologous expression, coupled with in vitro and in vivo models of bacterial pathogenesis, to demonstrate that the S. aureus pigment is a virulence factor and potential novel target for antimicrobial therapy.
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