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ENHANCED CHEMILUMINESCENT ENZYME-LINKED IMMUNOSORBENT ASSAY FOR DETECTION OF ANTIBODIES AGAINST BABESIA MICROTI

机译：增强的化学发光酶联免疫吸附法检测抗小肠杆菌的抗体

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摘要

Identification of immunodominant Babesia microti antigens using genome-wide immunoscreening is described. Candidate antigens were screened against sera from patients with clinical babesiosis. Also described are diagnostic assays with high sensitivity and specificity for detecting B.microti-specific antibodies in patient samples using the identified immunodominant antigens.

机译：描述了使用全基因组免疫筛选鉴定免疫性小肠杆状小球菌抗原的方法。从临床巴贝氏病患者的血清中筛选候选抗原。还介绍了使用鉴定出的免疫显性抗原以高灵敏度和特异性检测患者样品中的 微量抗体的诊断检测方法。 展开▼

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公开/公告号WO2019089936A1

专利类型

公开/公告日2019-05-09

原文格式PDF

申请/专利权人 THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY DEPARTMENT OF HEALTH AND HUMAN SERVICES;YALE UNIVERSITY;
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申请/专利号WO2018US58723

发明设计人 KUMAR SANJAI;VERMA NITIN;PURI ANKIT;KRAUSE PETER J.;
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申请日2018-11-01

分类号G01N33/569;

国家 WO

入库时间 2022-08-21 11:54:52

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