首页> 外国专利> PROBIOTIC FORMULATIONS FOR THE TREATMENT AND ALLEVIATION OF METABOLIC AND OXIDATIVE STRESS, INFLAMMATION AND NEURODEGENERATION

PROBIOTIC FORMULATIONS FOR THE TREATMENT AND ALLEVIATION OF METABOLIC AND OXIDATIVE STRESS, INFLAMMATION AND NEURODEGENERATION

机译:代谢和氧化应激,炎症和神经变性的治疗和缓解的概率公式

摘要

In alternative embodiments, provided are probiotic formulations, including compositions, formulations, products of manufacture and kits comprising them, and methods of using them, for the treatment and alleviation of metabolic and oxidative stress, inflammation and neurodegeneration. In alternative embodiments, probiotic formulations as provided herein comprise or consist of any combination of the three probiotic strains: Lactobacillus fermentum NCIMB 5221, Lactobacillus plantarum NCIMB 8826 and Bifidobacteria longum spp. infantis NCIMB 702255. In alternative embodiments, probiotic formulations as provided herein are combined with a triphala. In alternative embodiments, probiotic formulations as provided herein are used for: the treatment of metabolic conditions such as diabetes and obesity, inflammatory conditions such as IBD, IBS, arthritis; and, neurodegenerative diseases such as Alzheimer's disease and Parkinson's disease. In alternative embodiments, probiotic formulations as provided herein are used for: resisting oxidative stress, reducing inflammation, lowering blood and total glucose levels, lowering triglycerides levels and managing insulin resistance.
机译:在替代实施方案中,提供了益生菌制剂,包括组合物,制剂,包含它们的制造产品和试剂盒,以及使用它们的方法,用于治疗和缓解代谢和氧化应激,炎症和神经变性。在替代实施方案中,本文提供的益生菌制剂包含三种益生菌株的组合或由以下三种组合组成:发酵乳杆菌NCIMB 5221,植物乳杆菌NCIMB 8826和长双歧杆菌 spp。 <婴儿> NCIMB702255。在替代实施方案中,本文提供的益生菌制剂与三叶草组合。在替代的实施方案中,本文提供的益生菌制剂用于:代谢疾病如糖尿病和肥胖症的治疗,炎性疾病如IBD,IBS,关节炎的治疗;以及神经退行性疾病,例如阿尔茨海默氏病和帕金森氏病。在替代实施方案中,本文提供的益生菌制剂用于:抵抗氧化应激,减少炎症,降低血液和总葡萄糖水平,降低甘油三酸酯水平和控制胰岛素抵抗。

著录项

  • 公开/公告号WO2019157585A1

    专利类型

  • 公开/公告日2019-08-22

    原文格式PDF

  • 申请/专利权人 PROVIVA PHARMA INC.;

    申请/专利号WO2019CA00018

  • 发明设计人 WESTFALL SUSAN;PRAKASH SATYA;

    申请日2019-02-12

  • 分类号A61K35/747;A61K35/745;

  • 国家 WO

  • 入库时间 2022-08-21 11:53:32

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