NANOPARTICLES IN WHICH ANTIGEN PEPTIDE AND ADJUVANT ARE BOUND TO FERRITIN SELF ASSEMBLY, AND USE THEREOF

摘要

The present invention relates to ferritin nanoparticles to which an antigen peptide and an adjuvant are bound. Since an antigen peptide or an adjuvant are indirectly bound to a ferritin self assembly by using HTT^cys and V_L12.3^cys peptides, a fusion protein can be produced more easily than when an antigen and an adjuvant are directly fused, and also, the relative mole ratio of the antigen and the adjuvant can be readily adjusted, and thus the present invention can be effectively used as a vaccine composition.