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METHODS AND SYSTEMS FOR DETERMINING THE RISK OF DEVELOPING OVARIAN CANCER

机译:确定发展中的卵巢癌风险的方法和系统

摘要

The present invention relates to systems and methods for utilizing the measurement of two or more biomarkers to determine a probabilistic assessment for developing ovarian cancer. Particularly, aspects of the present invention are directed to a computer implemented method that includes obtaining, by a computing device, measured levels of two or more biomarkers in a sample obtained from a subject without knowledge of an ovarian mass or tumor in the subject, and determining, by the computing device, a probabilistic assessment of the subject developing ovarian cancer based on the obtained values. The coefficients of the logistic regression models used can take into account a time to diagnosis variable or unspecified omitted factors.
机译:本发明涉及用于利用两种或多种生物标志物的测定来确定发展卵巢癌的概率评估的系统和方法。特别地,本发明的方面针对一种计算机实现的方法,该方法包括通过计算设备获得从受试者获得的样品中两种或多种生物标志物的测量水平,而无需了解受试者的卵巢肿块或肿瘤,以及由所述计算设备基于所获得的值来确定对患有卵巢癌的受试者的概率评估。使用的逻辑回归模型的系数可以考虑诊断变量或未指定的遗漏因素的时间。

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