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Method for determining the risk of developing liver cancer, a kit for determining the risk of developing liver cancer, and a pharmaceutical composition

机译:用于确定发展为肝癌的风险的方法,用于确定发展为肝癌的风险的试剂盒以及药物组合物

摘要

PROBLEM TO BE SOLVED: To provide a method for determining a risk of developing liver cancer and a kit for determining the risk of developing liver cancer, which can determine the risk of developing liver cancer regardless of the hepatitis virus. A method for determining a risk of developing liver cancer, which comprises a step of measuring the content of a gelE gene or a gene product thereof in a target fecal sample. A kit for determining the risk of developing liver cancer, which comprises a reagent for measuring the content of the gelE gene in the target fecal sample. Further, a pharmaceutical composition for reducing the risk of developing liver cancer, which is administered to a subject determined to have a high risk of developing liver cancer by the method for determining the risk of developing liver cancer, and is a large intestine of the subject. A pharmaceutical composition comprising an agent that reduces the number of bacteria having the gelE gene within. [Selection diagram] None
机译:要解决的问题:提供一种确定发展为肝癌的风险的方法和一种试剂盒,用于确定发展为肝癌的风险,无论肝炎病毒如何,都可以确定发展为肝癌的风险。一种确定发展为肝癌的风险的方法,其包括测量目标粪便样品中的gelE基因或其基因产物的含量的步骤。用于确定患上肝癌的风险的试剂盒,包括用于测量目标粪便样品中gelE基因含量的试剂。此外,用于降低发展为肝癌的风险的药物组合物,其通过确定发展为肝癌的风险的方法施用于确定为具有发展为肝癌的高风险的受试者,并且是该受试者的大肠。药物组合物,其包含减少其中具有gelE基因的细菌数量的试剂。 [选择图]无

著录项

  • 公开/公告号JP2020130013A

    专利类型

  • 公开/公告日2020-08-31

    原文格式PDF

  • 申请/专利权人 国立大学法人金沢大学;

    申请/专利号JP20190025901

  • 申请日2019-02-15

  • 分类号C12Q1/686;A61K35/741;A61P35;A61K45;C12Q1/37;C12Q1/6851;C12N15/57;

  • 国家 JP

  • 入库时间 2022-08-21 11:37:39

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