GLYCONJUGATE VACCINES

摘要

This invention relates to the use of S. pneumoniaeprotein antigens, such as NanA, PiuA and Sp0148, as carriersfor immunogenic S. pneumoniaecapsular polysaccharide. This may be useful for example in glycoconjugate vaccinesable to generate a protective immune response against multiplecapsular serotypes.Glycoconjugates, vaccine compositions and methods of manufacture and use are provided.