MORI FOLIUM Extracts effective component for preventing and treating arthritis And Manufacturing Method of thereof

摘要

The present invention relates to a composition for preventing or ameliorating arthritis, which comprises an extract of Morus alba leaves. The extract of Morus alba leaves extracted with frozen Morus alba leaves at -130 to -60°C is included as an active ingredient. The use of the composition for preventing or ameliorating arthritis, which comprises the extract of Morus alba leaves, according to the present invention inhibits the expression of cytokines associated with osteoarthritis such as IL-1β, IL-6 and TNF-α, inhibits NO, COX-2, PGE2 and MMP expression, and inhibits cartilage damage. Therefore, the composition can prevent or ameliorate arthritis.