MORI FOLIUM Extracts effective component for preventing and treating arthritis And Manufacturing Method of thereof

摘要

The present invention is a composition for the prevention or improvement of arthritis, including the upper leaf extract comprises an upper leaf extract extracted with the upper leaf frozen at -130 to -60 ℃ as an active ingredient. When using a composition for the prevention or improvement of arthritis comprising the extract of the lobe according to the present invention, as well as inhibit the expression of cytokines associated with osteoarthritis such as IL-1β, IL-6 and TNF-α as well as iNOS, By inhibiting NO, COX-2, PGE ₂ and MMP expression, and inhibiting cartilage damage can be prevented or improved arthritis.