首页> 外国专利> DNA APPARATUS AND METHOD FOR DNA CONCENTRATION MEASUREMENT USING A NANOPORE SENSOR

DNA APPARATUS AND METHOD FOR DNA CONCENTRATION MEASUREMENT USING A NANOPORE SENSOR

机译:DNA仪器和使用纳米传感器测量DNA浓度的方法

摘要

The present invention provides an apparatus for measuring DNA concentration using a nanopore sensor, comprising: a vessel provided with a hole for inputting a DNA solution of which concentration is to be measured; a plurality of nanopore membranes dividing the vessel into serially connected separate spaces; a plurality of electrodes installed in each of the separate spaces; a power source unit applying voltage to the plurality of electrodes to enable the DNA to pass through the nanopore membranes and move; a detection unit measuring current of each ion passing through the plurality of nanopore membranes; and a calculation unit obtaining the DNA concentration from the measurement result of the detection unit. Each of the plurality of nanopore membranes is provided with one nanopore such that the DNA at a DNA solution input hole side of the vessel can arrive at an opposite side of the input hole through the nanopores of the plurality of nanopore membranes. The present invention improves shortages of a conventional DNA concentration apparatus to enhance accuracy, speed up analysis and perform convenient DNA concentration measurement without other special preparation.
机译:本发明提供了一种使用纳米孔传感器测量DNA浓度的设备,该设备包括:容器,其具有用于输入其浓度将被测量的DNA溶液的孔;以及容器。多个纳米孔膜将容器分成串联连接的独立空间;在每个单独的空间中安装多个电极;电源单元向多个电极施加电压,以使DNA能够通过纳米孔膜并移动。检测单元,其测量通过多个纳米孔膜的每个离子的电流;计算单元从检测单元的测量结果获得DNA浓度。多个纳米孔膜的每一个都设有一个纳米孔,使得容器的DNA溶液输入孔侧的DNA可以通过多个纳米孔膜的纳米孔到达输入孔的相对侧。本发明改善了常规DNA浓缩设备的不足,以提高准确性,加快分析速度并进行方便的DNA浓度测量而无需其他特殊准备。

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