首页> 外国专利> Method For Diagnosis of Diabetic Skin Diseases using the Concentration Of Skin Lipid Metabolites and Expression Level of Skin Lipid Biosynthesis Enzymes and Screening Method thereby

Method For Diagnosis of Diabetic Skin Diseases using the Concentration Of Skin Lipid Metabolites and Expression Level of Skin Lipid Biosynthesis Enzymes and Screening Method thereby

机译:利用皮肤脂质代谢物的浓度和皮肤脂质生物合成酶的表达水平诊断糖尿病皮肤病的方法及筛选方法

摘要

The present invention relates to a method for providing information for diagnosis or treatment of diabetic skin diseases, and to a screening method for a composition for treating the diabetic skin diseases, wherein the composition measures the expression level and activity of ceramidase in skin tissues of a subject to be examined on the diabetic skin diseases, and confirms the concentration of fatty acid and sphingosine, thereby being applicable as a marker for the screening method and the method for providing information.
机译:本发明涉及提供用于诊断或治疗糖尿病皮肤疾病的信息的方法,以及用于治疗糖尿病皮肤疾病的组合物的筛选方法,其中该组合物测量神经酰胺酶在皮肤组织中的表达水平和活性。糖尿病皮肤病的检查对象,并确认脂肪酸和鞘氨醇的浓度,从而可用作筛选方法和提供信息方法的标志物。

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