Use of nicotinic acid riboside or nicotinamide riboside derivatives and their reduced derivatives as precursors for increasing NAD +

摘要

(" NAR ") and its derivatives (1- (2 ', 3', 5 ' -trimethylammonium) Triacetyl-beta-D-ribofuranosyl) -nicotinic acid ("NAR triacetate" or "NARTA");(" NARH ") of a reduced form (" NARH ") of nicotinic acid or riboside of nicotinic acid (1- (2 ', 3 ', 5 ' -triacetyl-beta- D- ribofuranosyl) Triacetate " or " NARJT-TA "));(" NR triacetate " or " NRTA ") or nicotinamide ribose ("Lt; / RTI (2 ', 3', 5'-triacetyl-beta-D-ribofuranosyl) -1,4-dihydronickotinamide (" NRH triacetate " or " NRH-TA ")); Or salts or prodrugs thereof. ( ^& Quot; NAD ⁺ ") or NADH in cells and tissues in order to improve the survival of cells and tissues or the health of whole cells and tissues do.