首页> 外国专利> USE OF COMPOSITION CONTAINING STEM CELL-DERIVED EXOSOME AND/OR EXTRACELLULAR ENDOPLASMIC RETICULUM AS ACTIVE COMPONENT IN ALLEVIATING NON-ALCOHOLIC SIMPLE STEATOSIS OR NON-ALCOHOLIC STEATOHEPATITIS

USE OF COMPOSITION CONTAINING STEM CELL-DERIVED EXOSOME AND/OR EXTRACELLULAR ENDOPLASMIC RETICULUM AS ACTIVE COMPONENT IN ALLEVIATING NON-ALCOHOLIC SIMPLE STEATOSIS OR NON-ALCOHOLIC STEATOHEPATITIS

机译:包含干细胞源性外泌体和/或胞外内质网的组合物作为活性成分用于缓解非酒精性简单脂肪变性或非酒精性脂肪性肝炎

摘要

The present invention provides a stem cell-derived exosome and/or an extracellular endoplasmic reticulum, and a pharmaceutical composition containing at least one type selected from a group consisting of fractions containing the stem cell-derived exosome and/or the extracellular endoplasmic reticulum for preventing, relieving, alleviating, or treating non-alcoholic simple steatosis or non-alcoholic steatohepatitis. A composition of the present invention reduces or alleviates fat accumulation or inflammation in hepatocytes or liver tissues, which act as a cause of non-alcoholic simple steatosis or non-alcoholic steatohepatitis and alleviates, relieves or recovers a histological state of non-alcoholic simple steatosis or non-alcoholic steatohepatitis, thereby being able to prevent, relieve, alleviate or treat non-alcoholic simple steatosis or non-alcoholic steatohepatitis.;COPYRIGHT KIPO 2019
机译:本发明提供了一种干细胞来源的外来体和/或细胞外内质网,以及一种药物组合物,其包含至少一种选自由干细胞来源的外来体和/或细胞外内质网的级分组成的组中的用于预防,缓解,缓解或治疗非酒精性单纯脂肪变性或非酒精性脂肪性肝炎。本发明的组合物减少或减轻肝细胞或肝组织中的脂肪积累或炎症,这是非酒精性简单脂肪变性或非酒精性脂肪性肝炎的原因,并且减轻,减轻或恢复了非酒精性简单脂肪变性的组织学状态。或非酒精性脂肪性肝炎,从而能够预防,缓解,缓解或治疗非酒精性单纯性脂肪变性或非酒精性脂肪性肝炎。; COPYRIGHT KIPO 2019

著录项

  • 公开/公告号KR20190015063A

    专利类型

  • 公开/公告日2019-02-13

    原文格式PDF

  • 申请/专利权人 EXOCOBIO INC.;

    申请/专利号KR20170162555

  • 发明设计人 YI YONG WEONKR;CHO BYONG SEUNGKR;

    申请日2017-11-30

  • 分类号A61K35/28;A23L33/10;A61K35/51;A61K9;

  • 国家 KR

  • 入库时间 2022-08-21 11:51:37

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