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Method for enhancing potential of cytokine secretion of adipose-derived stem cells

机译:增强脂肪干细胞分泌细胞因子的潜力的方法

摘要

The present invention relates to a composition for promoting the secretion of cytokines of adipose-derived stem cells (ADSCs), which contains substance P as an active ingredient, and a method for promoting cytokine secretion of ADSC using the same. The present invention also relates to a conditioned medium of ADSC prepared by using substance P, a method for preparing the same, and a composition for immunosuppression or angiogenesis comprising the same as an active ingredient. According to the present invention, since substance P effectively promotes the cytokine secretion ability of ADSC, the conditioned medium of ADSC cultured together with substance P shows excellent effects on immunosuppressive ability and angiogenesis.
机译:本发明涉及一种用于促进脂肪干细胞(ADSC)的细胞因子分泌的组合物,其包含物质P作为活性成分,以及使用该组合物促进ADSC的细胞因子分泌的方法。本发明还涉及通过使用物质P制备的ADSC条件培养基,其制备方法以及包含其作为活性成分的免疫抑制或血管生成组合物。根据本发明,由于物质P有效地促进了ADSC的细胞因子分泌能力,因此与物质P一起培养的ADSC的条件培养基对免疫抑制能力和血管生成具有优异的作用。

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