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Method for enhancing potential of cytokine secretion of adipose-derived stem cells

机译:增强脂肪干细胞分泌细胞因子的潜力的方法

摘要

The present invention relates to a composition for enhancing cytokine secretion of ADSC (adipose-derived stem cell), comprising a substance P as an active ingredient, and a method for enhancing cytokine secretion of ADSC using the same. The present invention also relates to a conditioned medium of ADSC prepared using Substance P, a preparation method thereof, and an immunosuppressive or angiogenic composition comprising the same as an active ingredient. According to the present invention, the substance P effectively enhances the cytokine secretion ability of ADSC, and the adjusted medium of the ADSC cultured with the substance P shows an excellent effect on enhancing immune suppression ability and angiogenesis.
机译:本发明涉及用于增强ADSC(脂肪干细胞)的细胞因子分泌的组合物,其包含物质P作为活性成分,以及使用该组合物增强ADSC的细胞因子分泌的方法。本发明还涉及使用物质P制备的ADSC的条件培养基,其制备方法以及包含其作为活性成分的免疫抑制或血管生成组合物。根据本发明,物质P有效地增强了ADSC的细胞因子分泌能力,并且与物质P一起培养的ADSC的调节培养基显示出了增强免疫抑制能力和血管生成的优异效果。

著录项

  • 公开/公告号KR102054940B1

    专利类型

  • 公开/公告日2019-12-11

    原文格式PDF

  • 申请/专利权人 경희대학교 산학협력단;

    申请/专利号KR20170142381

  • 发明设计人 손영숙;홍현숙;

    申请日2017-10-30

  • 分类号C12N5/0775;

  • 国家 KR

  • 入库时间 2022-08-21 11:08:22

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