Pharmaceutical composition to prevent opioid poisoning

摘要

Pharmaceutical compositions for preventing opioid poisoning in a patient are disclosed. The composition can be used in patients suffering from moderate to severe low back pain (LBP). The composition is useful for patients diagnosed with low back pain and comprises a therapeutically effective amount of an antibody or antigen-binding fragment thereof that specifically binds to nerve growth factor (NGF); Use in the absence of opioids relieves pain in patients and prevents opioid poisoning.