Benzisothiazole, isothiazolo 3,4-B pyridine, quinazoline, phthalazine, pyrido 2,3-D pyridazine, as KRAS G12C inhibitors for the treatment of lung cancer, pancreatic cancer or colon cancer Pyrido 2,3-D pyrimidine derivatives

摘要

Benzisothiazole, isothiazolo [3,4-b] pyridine, quinazoline, phthalazine, pyrido [2,3-d as KRAS G12C inhibitors for the treatment of lung cancer, pancreatic cancer or colorectal cancer, for example. ] Pyridazine and pyrido [2,3-d] pyrimidine derivatives and related compounds are provided herein.