Benzisothiazole, isothiazole 3,4-b pyridine, quinazoline, phthalazine, pyrido 2,3-d pyridazine and as KRAS G12C inhibitors for the treatment of lung, pancreatic, or colorectal cancer Pyrid 2,3-d pyrimidine derivative

摘要

As used herein, for example, benzisothiazole, isothiazolo [3,4-b] pyridine, quinazoline, phthalazine, pyrido as a KRAS G12C inhibitor for treating lung, pancreatic or colon cancer. 2,3-d] pyridazine and pyrido [2,3-d] pyrimidine derivatives and related compounds are provided.