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134- 134-oxadiazole derivative a method for producing the same and an anticancer drug containing the same
134- 134-oxadiazole derivative a method for producing the same and an anticancer drug containing the same
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机译:134-134-恶二唑衍生物及其制备方法和含有该衍生物的抗癌药
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摘要
The present invention relates to a 1,3,4-oxadiazole derivative, a method of producing the same, and an anticancer agent comprising the same. In particular, the compound according to the present invention can be represented by chemical formula 1, and may be useful as an anticancer agent due to excellent anticancer activities. In the chemical formula 1, R^1 is F, Br, methoxy, phenyl, or pyridinyl; and R^2 is H or methoxy, wherein the chemical formula 1 excludes the following three compounds: 1) 3-(5-phenyl-1,3,4-oxadiazol-2-yl)-4H-chromene-4-on; 5) 3-(5-(pyridin-3-yl)-1,3,4-oxadiazol-2-yl)-4H-chromene-4-on; and 6) 3-(5-(pyridin-4-yl)-1,3,4-oxadiazol-2-yl)-4H-chromene-4-on.
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机译:1,3,4-恶二唑衍生物,其制备方法以及包含该衍生物的抗癌剂涉及本发明。特别地,根据本发明的化合物可以由化学式1表示,并且由于优异的抗癌活性而可以用作抗癌剂。在化学式1中,R ^ 1为F,Br,甲氧基,苯基或吡啶基; R 2为H或甲氧基,化学式1不包括以下三种化合物:1)3-(5-苯基-1,3,4-恶二唑-2-基)-4H-色烯-4-上; 5)3-(5-(吡啶-3-基)-1,3,4-恶二唑-2-基)-4H-色烯-4-上; 6)3-(5-(吡啶-4-基)-1,3,4-恶二唑-2-基)-4H-色烯-4-上。
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