Method for diagnosis of chronic obstructive airway disease using analysis of bacteria metagenome

摘要

The present invention relates to a method for diagnosing chronic obstructive airways diseases such as asthma and COPD through the analysis of bacterial metagenomes. More specifically, the present invention relates to a method for diagnosing chronic obstructive airways diseases such as COPD, And a method for diagnosing chronic obstructive pulmonary disease and asthma by analyzing the increase and decrease of the content. The extracellular vesicles secreted from bacteria in the environment are absorbed into the body and can directly affect the inflammation. Since chronic obstructive airways diseases such as asthma and COPD are difficult to diagnose before the symptoms occur, effective treatment is difficult , The risk of chronic obstructive airway disease such as asthma and COPD is predicted by analyzing the meta genome of the gene existing in the extracellular vesicles derived from bacteria using the sample derived from human body according to the present invention, And it is possible to prevent the onset or prevent the onset through appropriate management and to diagnose early after the onset of chronic obstructive airway diseases such as asthma and COPD, thereby lowering the incidence of the disease and improving the therapeutic effect.