PROCESS FOR THE PREPARATION OF AROMATIC THIOL DERIVATIVES BY HYDROGENATION OF DISULFIDES

摘要

The present invention relates to the preparation of thiophenols by reacting the corresponding disulfides with hydrogen in the presence of a heterogeneous transition metal hydrogenation catalyst. When the reaction is carried out in the presence of an acylating agent, such as a carboxylic acid anhydride or a halide, an acylated thiophenol is obtained. S- [2- [1- (2-ethylbutyl) -cyclohexanecarbonylamino] -phenyl] 2-methylthiopropionate, which is a pharmaceutically active compound, is produced through this process.