A Method for Inducing Enhanced Adhesions and Osteogenesis on Mesenchymal Stem cells using magnetic field

摘要

The present invention relates to a method for inducing cell adhesion and differentiation of a stem cell using a magnetic field, and more particularly, to a method for intermittently treating a magnetic field in a culture dish in a range of 100 mT to 160 mT per day A method for increasing the proliferation rate of stem cells, comprising intermittently treating the culture dish in a range of 100 mT to 160 mT per day in a culture dish at the time of stem cell culture, and The present invention relates to a method for promoting osteogenic differentiation of mesenchymal stem cells, comprising intermittently treating a culture dish in a range of 50 mT to 260 mT at 1 day in the culture of stem cells. The present invention also provides methods of modulating morphogenesis of increased attachment and bone formation to hABMSCs by synergistic induction of magnetic fields, and methods of expressing protein factors known to stimulate bone formation by magnetic field treatment.