Composition for Prevention or Treatment of Mental Disorders Comprising Extracellular Vesicles Derived from Lactobacillus

摘要

The present invention relates to a composition for preventing, ameliorating, or treating a mental disorder, which comprises a bacterium-derived vesicle of the genus Lactobacillus as an effective ingredient. The inventors of the present invention have found that when the vesicles derived from bacteria belonging to the genus Lactobacillus are administered to an animal model of stress and depression, the resistance to stress is effectively increased and the effect of treating chronic depressive behavior for a long period of time is proved. Of the bacteria of the genus Lactobacillus according to the present invention are used for preventing, symptomatic or treating a mental disorder such as stress, anxiety disorder, posttraumatic stress disorder, panic disorder, depression, autism spectrum disorder, attention deficit hyperactivity syndrome, It is expected to be useful for the development of medicines or health functional foods.