首页> 外国专利> - - - Preparing L-ribulose and L-ribose based on L-Arabinose

- - - Preparing L-ribulose and L-ribose based on L-Arabinose

机译:---基于L-阿拉伯糖制备L-核糖和L-核糖

摘要

The present invention relates to a method for producing el-ribose based on el-arabinose, and more specifically, to produce an el-ribose by culturing a first microorganism in which an el-ribose production pathway is introduced from arabinose in a medium containing arabinose. Making a step; After removing the first microorganism from the culture medium, inoculating and incubating the second microorganism into which the L-ribulose metabolic pathway was introduced, consuming the L-arabinose and the L-ribulose, and then producing the resulting L-ribose Recovering. The method of producing el-ribose according to the present invention removes all sugars except for el-ribose in metabolism, so that it is possible to produce high-purity el-ribose from fermented products, and the produced ribose is various L-forms. It is useful because it can be usefully used in the manufacture of medicines as a starting material for the synthesis of pharmaceutical products per sugar nucleic acid.
机译:本发明涉及基于阿拉伯糖的生产核糖的方法,更具体地,涉及通过在含有阿拉伯糖的培养基中培养从阿拉伯糖引入了核糖生产途径的第一微生物来生产核糖的方法。 。迈出一步;从培养基中去除第一微生物后,接种并孵育引入了L-核糖代谢途径的第二微生物,消耗L-阿拉伯糖和L-核糖,然后产生所得的L-核糖回收。根据本发明的生产核糖核糖的方法除去了代谢中的核糖核糖以外的所有糖,因此可以从发酵产物生产高纯度的核糖核糖,并且所生产的核糖为各种L-形式。这是有用的,因为它可以作为每个糖核酸合成药物产品的起始原料有效地用于药物的生产。

著录项

  • 公开/公告号KR102019220B1

    专利类型

  • 公开/公告日2019-09-06

    原文格式PDF

  • 申请/专利权人 한국과학기술원;

    申请/专利号KR1020180155019

  • 发明设计人 김정회;심우용;여인석;

    申请日2018-12-05

  • 分类号C12N9/90;C12N15/81;C12P19/02;

  • 国家 KR

  • 入库时间 2022-08-21 11:47:47

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