Derivatives of coumarin, thiocoumarin and quinolinone with anticonvulsant activity

摘要

FIELD: medicine; pharmaceuticals.SUBSTANCE: invention relates to derivatives of (coumarin-4-yl) aminocarboxylic acids, (thiocoumarin-4-yl) aminocarboxylic acids and (2-oxo-1,2-dihydroquinolin-4-yl) aminocarboxylic acids. In formulas 1.1–1.3, R is hydrogen or a nitro group; X is O, S or NH; Y is OH, OCH, OCH, NHor NHCH. Invention also relates to methods for preparing said compounds and a method of treating epilepsy and paroxysmal conditions using said compounds.EFFECT: can be used in treating epilepsy and paroxysmal conditions.13 cl, 5 tbl, 13 ex