首页> 外国专利> APPLICATION OF CONJUGATED LINOIC ACID OR ITS DERIVATIVES FOR OBTAINING ACETALDEHYDEHYDROHYDROGENASE ACTIVATOR

APPLICATION OF CONJUGATED LINOIC ACID OR ITS DERIVATIVES FOR OBTAINING ACETALDEHYDEHYDROHYDROGENASE ACTIVATOR

机译:共轭亚麻酸或其衍生物在乙醛加氢加氢酶活化剂中的应用

摘要

The invention belongs to the field of biological medicines, and relates to an application of conjugated linoleic acid or derivatives thereof in the aspect of preparing an acetaldehyde dehydrogenase activity accelerant and alcoholic liver injury relieving preparations. The invention provides the novel application of the conjugated linoleic acid or the derivatives thereof (in particular conjugated linoleic acid glyceride); and based upon animal experiments, it proves that the conjugated linoleic acid or the derivatives thereof can improve the activities of liver acetaldehyde dehydrogenase and cytochrome P4502E1 and can relieve the pathological change degree of liver with alcoholic liver injury.
机译:本发明属于生物医学领域,涉及共轭亚油酸或其衍生物在制备乙醛脱氢酶活性促进剂和减轻酒精性肝损伤的制剂中的应用。本发明提供了共轭亚油酸或其衍生物(特别是共轭亚油酸甘油酯)的新应用。并通过动物实验证明,共轭亚油酸或其衍生物可以改善肝乙醛脱氢酶和细胞色素P4502E1的活性,可以减轻酒精性肝损伤后肝脏的病理变化程度。

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