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CALCIUM SENSING RECEPTORS, LIGANDS, COMPOSITIONS, AND METHODS OF USE

机译:钙敏感受体,液体,成分和使用方法

摘要

Described herein are compounds that can bind CaSR and/or a CaSR extracellular domain and formulations thereof. Also described herein are methods of inhibiting CaSR and/or treating a disease or disorder associated with a mutation in CaSR by administering a compound or formulation thereof described herein. Also described herein are assays that can be used to identify compounds that can bind an extracellular domain of CaSR.
机译:本文描述了可以结合CaSR和/或CaSR胞外域的化合物及其制剂。本文还描述了通过施用本文所述的化合物或其制剂来抑制CaSR和/或治疗与CaSR突变相关的疾病或病症的方法。本文还描述了可用于鉴定可结合CaSR胞外域的化合物的测定法。

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