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SYNERGISTIC COMPOSITIONS COMPRISING (R)-DIMIRACETAM (1) AND (S)-DIMIRACETAM (2) IN A NON-RACEMIC RATIO

机译:在非主成分比例中包含(R)-二甲双胍(1)和(S)-二甲双胍(2)的协同组成

摘要

The present invention relates to a composition of enantiomers of 3,6,7,7a-tetrahydro-1H-pyrrolo[1,5-a]imidazole-2,5-dione and pharmaceutically acceptable solvates or co-crystals thereof in a certain ratio, a pharmaceutical composition comprising said composition, its use as a medicament and the use of the inventive compositions or pharmaceutical compositions in the treatment and/or prevention of a disease or disorder typically and preferably selected from peripheral sensory neuropathy, preferably peripheral neuropathic pain; seizure; depression; or cognitive impairment.
机译:3,6,7,7a-四氢-1H-吡咯并[1,5-a]咪唑-2,5-二酮的对映异构体及其药学上可接受的溶剂化物或共晶体[0017]包含所述组合物的药物组合物,其作为药物的用途以及本发明的组合物或药物组合物在治疗和/或预防疾病或病症中的用途,所述疾病或病症通常且优选选自周围感觉神经病,优选周围神经性疼痛;发作;萧条;或认知障碍。

著录项

  • 公开/公告号EP3534898B1

    专利类型

  • 公开/公告日2020-08-05

    原文格式PDF

  • 申请/专利权人 METYS PHARMACEUTICALS AG;

    申请/专利号EP20180728356

  • 发明设计人 SCHERZ MICHAEL;FARINA CARLO;

    申请日2018-05-30

  • 分类号A61K31/4188;A61P25/02;A61P25/24;A61P25/28;A61K31/7068;A61K31/7072;A61K31/708;A61K45/06;

  • 国家 EP

  • 入库时间 2022-08-21 11:41:24

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