DIAGNOSTIC AND TREATMENT OF CHRONIC PATHOLOGIES SUCH AS LYME DISEASE

摘要

The present invention relates to several biomarkers, including IL-1RA, IFN-³ and GM-CSF, whose expressions at the mRNA level and at the protein level, correlate with chronic pathologies, such as Lyme disease, in particular the late chronic form of Lyme disease. More specifically, the invention provides methods and kits for the diagnosis of such chronic pathologies and for the assessment of a patient's response to a treatment, as well as methods and therapeutic agents for the treatment of such chronic pathologies.