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MUTATED CELLOBIOSE DEHYDROGENASE WITH MODIFIED SUBSTRATE SPECIFICITY
MUTATED CELLOBIOSE DEHYDROGENASE WITH MODIFIED SUBSTRATE SPECIFICITY
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机译:修饰的底物特异性突变型纤维素酶脱氢酶
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摘要
The present invention relates to a modified cellobiose dehydrogenase (CDH) or its functional flavodehydrogenase domain having a substitution at the amino acid corresponding to N721 of SEQ ID NO: 5 (CDH from M . thermophilum ) by glutamine, isoleucine, threonine or leucine or a substitution of the asparagine in the active canter motif having the amino acid sequence NHW by glutamine, isoleucine, threonine or leucine.
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机译:本发明涉及修饰的纤维二糖脱氢酶(CDH)或其功能性黄酮脱氢酶结构域,其在对应于SEQ ID NO:5的N721的氨基酸(嗜热毁丝霉的CDH)的氨基酸上被谷氨酰胺,异亮氨酸,苏氨酸或亮氨酸取代或谷氨酰胺,异亮氨酸,苏氨酸或亮氨酸取代具有氨基酸序列NHW的活性慢跑基序中的天冬酰胺。
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