首页> 外国专利> An immunochromatographic test strip for extracting and measuring a sugar chain antigen capable of controlling the development of a sample by impregnating a hydrophobic material with nitrite or a solid acidic reagent

An immunochromatographic test strip for extracting and measuring a sugar chain antigen capable of controlling the development of a sample by impregnating a hydrophobic material with nitrite or a solid acidic reagent

机译:一种用于提取和测量糖链抗原的免疫色谱试纸,该试纸能够通过用亚硝酸盐或固体酸性试剂浸渍疏水材料来控制样品的发育

摘要

PROBLEM TO BE SOLVED: To provide an immunochromatographic test strip for controlling the development of a sample on an immunochromatographic test strip and appropriately controlling the treatment with an acidic reagent, a nitrite and a neutralizing reagent, and an immunochromatographic method using the test strip. The purpose is to provide. A sample pad to which a specimen mixed with a nitrite or an acidic solution is added, a labeled region containing a labeled antibody labeled with an antibody against a sugar chain antigen, and a detection region immobilized with an antibody against the sugar chain antigen are included. An immunochromatographic test strip for measuring a sugar chain antigen by forming a complex of antibody-sugar chain antigen-labeled antibody in the detection area, which has an area impregnated with a neutralizing reagent upstream of the labeled body area. Further, upstream of the region impregnated with the neutralizing reagent, there is a region impregnated with a solid acidic reagent when using a sample mixed with nitrite, and when the sample mixed with an acidic solution is used, impregnated with nitrite. An immunochromatographic test strip for extracting and measuring a sugar chain antigen in a specimen, which has a region made to have a characteristic that a hydrophobic material is used in a region impregnated with nitrite or a solid acidic reagent. , Immunochromatographic test piece. [Selection diagram] None
机译:解决的问题:提供一种免疫色谱测试条,用于控制免疫色谱测试条上的样品的显影并适当地控制用酸性试剂,亚硝酸盐和中和剂的处理,以及使用该测试条的免疫色谱方法。目的是提供。包括添加有与亚硝酸盐或酸性溶液混合的样本的样品垫,包含用抗糖链抗原的抗体标记的标记抗体的标记区域和固定有抗糖链抗原的抗体的检测区域。 。一种通过在检测区域中形成抗体-糖链抗原标记的抗体的复合物来测量糖链抗原的免疫色谱试纸,该检测区域在被标记的身体区域上游具有被中和试剂浸透的区域。此外,在使用中和剂浸渍的区域的上游,当使用混合有亚硝酸盐的样品时,存在浸有固体酸性试剂的区域,而当使用混合有酸性溶液的样品时,则是用亚硝酸盐浸渍的区域。一种用于提取和测量样品中糖链抗原的免疫色谱测试条,其具有的区域具有在用亚硝酸盐或固体酸性试剂浸渍的区域中使用疏水性材料的特征。 ,免疫层析试片。 [选择图]无

著录项

  • 公开/公告号JP2020122663A

    专利类型

  • 公开/公告日2020-08-13

    原文格式PDF

  • 申请/专利权人 デンカ生研株式会社;

    申请/专利号JP20190012974

  • 发明设计人 加藤 大介;村松 志野;

    申请日2019-01-29

  • 分类号G01N33/543;G01N33/53;G01N33/569;

  • 国家 JP

  • 入库时间 2022-08-21 11:37:50

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