NEUTRALIZING ANTIBODIES TO MAJOR EXOTOXINS TcdA AND TcdB OF CLOSTRIDIUM DIFFICILE

摘要

To provide: the derivation and selection of antibodies capable of neutralizing major exotoxins TcdA and TcdB of Clostridium difficile; and novel neutralization and antigen binding properties of individual Mabs and mixtures thereof.SOLUTION: The present invention describes the derivation and selection of antibodies capable of neutralizing major exotoxins TcdA and TcdB of Clostridium difficile. The invention also describes novel neutralization and antigen binding properties of individual Mabs and mixtures thereof.SELECTED DRAWING: None