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Influenza virus production cells and influenza virus production method

机译:流感病毒产生细胞和流感病毒产生方法

摘要

PROBLEM TO BE SOLVED: To produce an influenza virus by using an in vitro culturable cell which has a high proliferative ability of the influenza virus and is preferably used for producing an influenza virus for vaccine production. Provide a way to do it. According to the present invention, an influenza virus-producing cell and a TMED2 gene in a chromosome, characterized in that the expression of the TMED2 gene in the chromosome is suppressed and the cell can be cultured in vitro. Influenza virus, which is characterized in that cells whose expression is suppressed and which can be cultured in vitro (excluding cells constituting humans themselves) are infected with the influenza virus and then cultured. It is a production method. [Selection diagram] None
机译:解决的问题:通过使用体外培养细胞来生产流感病毒,该细胞具有高的流感病毒增殖能力,并且优选用于生产用于疫苗生产的流感病毒。提供一种实现方法。根据本发明,产生流感病毒的细胞和染色体中的TMED2基因,其特征在于,染色体中TMED2基因的表达被抑制,并且可以在体外培养该细胞。流感病毒的特征在于,将表达受到抑制并且可以在体外培养的细胞(不包括构成自身的细胞)感染流感病毒,然后进行培养。这是一种生产方法。 [选择图]无

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