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Methods and kits for predicting esophageal cancer response to anti-ERBB3 antibody treatment

机译:预测食管癌对抗ERBB3抗体反应的方法和试剂盒

摘要

The present invention is a method for predicting whether esophageal cancer is susceptible or resistant to treatment with an ERBB3 inhibitor (eg, an anti-ERBB3 antibody), and specifically, SDC, PTGES, NCF2, NOXA1. Disclosed is a method of predicting by measuring the expression of RNA level or protein level in a tumor sample of at least one marker selected from CARD6, CARD6 and GNAZ. [Selection diagram] Fig. 12
机译:本发明是一种预测食道癌是否对ERBB3抑制剂(例如抗ERBB3抗体),特别是SDC,PTGES,NCF2,NOXA1的治疗敏感或耐药的方法。公开了一种通过测量至少一种选自CARD6,CARD6和GNAZ的标志物的肿瘤样品中RNA水平或蛋白质水平的表达进行预测的方法。 [选择图]图12

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